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    General information: [ref]

    Combipres (Clonidine Hydrochloride, Chlorthalidone)Clonidine with Chlorthalidone (trade names include Combipres; Catapres Diu; Clorpres; Clothalton; Combipresan; Combipress) is a combined antihypertensive medication from imidazoline receptor agonists (Clonidine) and low-ceiling diuretics (Chlorthalidone) pharmacological groups. This medicine is used for the treatment of hypertension (high blood pressure, HBP). Lowering high blood pressure helps prevent heart attacks, strokes, and kidney problems. Clonidine works by relaxing blood vessels so blood can flow more easily. Chlorthalidone is a diuretic or "water pill" and causes your body to get rid of extra salt and water. Combipres is indicated alone or in combinations with other antihypertensive drugs.


    Pharmacological and medical categories:

  • Antihypertensive drugs
  • Antisympathotonic agents
  • Cardiovascular medicines
  • Combined antihypertensive medications


    The Anatomical Therapeutic Chemical (ATC) classification system codes:

  • C - Cardiovascular system
  • C02 - Antihypertensives
  • C02L - Antihypertensives and diuretics in combination
  • C02LC - Imidazoline receptor agonists in combination with diuretics
  • C02LC01 - Clonidine and diuretics


    The International Statistical Classification of Diseases and Related Health Problems (World Health Organization, ICD-10) codes:

  • Essential (primary) hypertension - I10


    Pregnancy categories:

  • B - Australia
  • C - United States (Risk cannot be ruled out)


    Salts and other forms used as active pharmaceutical ingredients (API):

  • Clonidine Base with Chlorthalidone
  • Clonidine Hydrochloride with Chlorthalidone


    Synonyms, international and chemical names:

  • Chlornidinum
  • Clonidin
  • Clonidina
  • Clonidinum
  • Klonidiini
  • Klonidin
  • Klonidine
  • Klonidyna

  • Chlorothalidone
  • Chlorphthalidolone
  • Chlorphthalidone
  • Chlortalidone
  • Chlortalidonum
  • Chlorthalidon
  • Clortalidona
  • Clortalidone
  • Phthalamodine
  • Phthalamudine


    Brands, generics, trade names in various countries:

  • Catapres Diu - Boehringer Ingelheim; German Remedies; Zydus Cadila
  • Clorpres - Mylan; Bertek Pharmaceuticals
  • Clothalton - Sarabhai Piramal Pharma; Nicholas Piramal
  • Combipres - Boehringer Ingelheim
  • Combipresan - Boehringer Ingelheim
  • Combipress - Boehringer Ingelheim


    Pharmaceutical drugs and active ingredients (APIs) used in health care in combinations with clonidine and chlorthalidone:

  • Betaxolol
  • Bopindolol
  • Hydralazine
  • Hydrochlorothiazide
  • Labetalol
  • Metoprolol
  • Oxprenolol
  • Proxodolol
  • Reserpine
  • Triamterene


    Some other medications in the same pharmacological classes:

  • Aceon (Perindopril Erbumine)
  • Adalat (Nifedipine)
  • Altace (Ramipril)
  • Avalide (Irbesartan; Hydrochlorothiazide)
  • Avapro (Irbesartan)
  • Benicar (Olmesartan)
  • Calan (Verapamil)
  • Cardura (Doxazosin)
  • Cartia (Diltiazem)
  • Catapres (Clonidine)
  • Colospa (Mebeverine)
  • Diovan (Valsartan)
  • Hyzaar (Losartan; Hydrochlorothiazide)
  • Inderal (Propranolol)
  • Lopressor (Metoprolol)
  • Mestinon (Pyridostigmine)
  • Norvasc (Amlodipine)
  • Robaxin (Methocarbamol)
  • Tenormin (Atenolol)
  • Topamax (Topiramate)
  • Toprol-XL (Metoprolol)
  • Vaseretic (Enalapril; Hydrochlorothiazide)
  • Vasotec (Enalapril)
  • Zanaflex (Tizanidine)
  • Zebeta (Bisoprolol)
  • Zestril (Lisinopril)


    References:

  • PubChem database with main scientific information about active pharmaceutical ingredients : https://pubchem.ncbi.nlm.nih.gov/
  • PubMed database on US National Library of Medicine, National Institutes of Health: https://www.ncbi.nlm.nih.gov/pubmed/
  • DrugBank database containing information on drugs and drug targets: https://www.drugbank.ca/
  • MedlinePlus - an online information service produced by the United States National Library of Medicine: https://medlineplus.gov/
  • WebMD - an online publisher of news and information pertaining to human health and well-being: https://www.webmd.com/
  • Medscape - a website providing access to medical information for physicians and health professionals: https://www.medscape.com/
  • DailyMed drug labels resource from U.S. National Library of Medicine: https://dailymed.nlm.nih.gov/dailymed/spl-resources-all-drug-labels.cfm
  • Mayo Clinic - a nonprofit academic medical center focused on integrated clinical practice, education, and research: https://www.mayoclinic.org/
  • Drugs@FDA: U.S. Food and Drug Administration approved drug products database: https://www.accessdata.fda.gov/scripts/cder/daf/
  • Drug Product Database online query from Health Canada: https://health-products.canada.ca/dpd-bdpp/index-eng.jsp
  • European Medicines Agency (EMA) website with "Search for medicines" tool for European Union countries: https://www.ema.europa.eu/en
  • UK drug database from electronic Medicines Compendium (eMC): https://www.medicines.org.uk/emc
  • Australian medicine finder from NPS MedicineWise: https://www.nps.org.au/medicine-finder
  • Agencia Espanola de Medicamentos y Productos Sanitarios - AEMPS: https://www.aemps.gob.es/
  • Pharma and medical DB in EU on CBG-MEB: https://www.cbg-meb.nl/
  • Huge database for drug search especially for european and Latin America region: https://www.vademecum.es/equivalencia
  • MyHealthbox - multilanguage search engine for official information on medicines and healthcare products: https://myhealthbox.eu/en/
  • Pharmaceutical and other healthcare databases in some countries, primarily across Asia Pacific: https://www.mims.com/
  • MIMS drug index in China: http://www.mims.com.cn/china/drug/index/
  • IndiaMart - Various exploring tools, including for medical and pharmaceutical products in India: https://dir.indiamart.com/
  • A to Z brands and generics with their comparative prices on MedGuideIndia: http://www.medguideindia.com/show_generics.php
  • Generic drugs with their brand names on Medindia: https://www.medindia.net/drug-price/index.asp
  • Online Drug Information System, primarily for India and Pakistan: http://www.druginfosys.com/
  • Medizzine - hispanic portal for medicines: http://www.medizzine.com/pacientes/medicamentos/index.php
  • English version of Medizzine - health & medicines portal: http://www.medizzine.com/en/patients/drugs/index.php
  • Search tools for medications on Japanese Orange Book: http://www.jp-orangebook.gr.jp/cgi-bin/search/search_e.cgi
  • South Korean PharmaLink gateway: http://www.pharmalink.kr/
  • Medicines brand and generic index for Africa region: https://daktariafrica.com/medicine/raw/index/
  • APIs database on Galinos: https://www.galinos.gr/web/drugs/main/substances
  • RLSNet index for drugs, nutritions and supplements in Russia, Eastern Europe and Middle Asia regions: https://www.rlsnet.ru/tn_alf.htm
  • Taiwan Food and Drug Administration: https://www.fda.gov.tw/TC/index.aspx
  • Online medicine information directory from MedEx: https://medex.com.bd/generics/
  • The Anatomical Therapeutic Chemical ATC/DDD Index 2019: https://www.whocc.no/atc_ddd_index/
  • International Statistical Classification of Diseases and Related Health Problems 10th Revision, WHO: https://www.icd10data.com/

    Updated: September, 2019



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